I.R.C.C.S. Besta Milan (Italy) – Neuroimmunology and Neuromuscular Diseases Unit

Renato Mantegazza


Dr. Renato Mantegazza has a long-lasting experience in the field of Myasthenia Gravis (MG), Neuromuscular Junction Diseases (such as Lambert-Eaton Myasthenic Syndrome), Multiple Sclerosis, Motor Neuron Diseases and Inflammatory Myopathies by giving contributions in the understanding of the pathogenic mechanisms underlying these diseases and in their treatments. Dr. Mantegazza professional and scientific training was developed at the Weizmann Institute of Science (Israel), Stanford University (USA). His scientific production consists of more than 100 peer-reviewed publications.

He is the Director of the Neuroimmunology and Neuromuscular Diseases Unit at the Fondazione Istituto Neurologico “Carlo Besta” of Milan. The Department activity is focused on the diagnostics, treatment and research of immune-mediated neurological diseases as well as neuromuscular, motor neuron and muscular disorders. The Department hosts biobanks for sera/plasma/CSF, muscle/myoblasts, thymus/thymic cell lines, peripheral blood mononuclear cells, fibroblasts/iPSCs, and nucleic acids from a large number of MS and MG/LEMS patients.

Dr. Mantegazza has been appointed as the Director of the Clinical Research Department for the Istituto Neurologico “Carlo Besta” and is PI of several clinical trials in Multiple Sclerosis and Myasthenia Gravis. Dr. Renato Mantegazza is part of Scientific Advisory Boards of Biomarin, Alexion Pharmaceuticals, ARGX and TEVA Italia.