I.R.C.C.S. Besta, Milan (Italy) – Rare Neurodegenerative and Neurometabolic Diseases Unit, Department of Clinical Neurosciences

Davide Pareyson


Davide Pareyson is a Clinical Neurologist working at the Fondazione IRCCS Istituto Neurologico C.Besta (INCB) of Milan, Italy, where he is currently Head of the Rare Neurodegenerative and Neurometabolic Diseases Unit; he is also Chief of the Functional Department of Rare Neurological Diseases.
His main interest is clinical research on hereditary and acquired peripheral neuropathies and motor neuronopathies, inherited neurological disorders, rare diseases. He performed studies on phenotype-genotype correlation, clinical findings, electrophysiology, neuropathology of hereditary neuropathies (particularly Charcot-Marie-Tooth disease – CMT – and related neuropathies, but also amyloid neuropathy) and other neurogenetic disorders including spinal and bulbar muscle atrophy, hereditary spastic paraplegias, hereditary ataxias, genetic leukodystrophies.
He has been working on the development of outcome measures for hereditary neuropathies and other rare diseases and has coordinated and participated in clinical trials and natural history studies in inherited and acquired neuropathies. He coordinated the international trial on ascorbic acid in CMT1A in Italy and UK (Pareyson et al., Lancet Neurol 2011) and the observational trial in patients with ATTR amyloid neuropathy treated with tafamidis (Cortese et al., J Neurol 2016). He participated in other interventional trials including the following: CMT (comparing two different rehabilitative approaches in CMT, coordinated by A Schenone, Genoa), CIDP (one coordinated by E Nobile Orazio with IVIG and pulse steroids, E Nobile-Orazio et al., Lancet Neurol 2015, and one international coordinated by RAC Hughes, published on Lancet Neurol 2012).
He is the Coordinator of the Italian National Registries of Charcot-Marie-Tooth disease and of Spino-Bulbar Muscular Atrophy (www.registronmd.it).
He is among the organizers of three ENMC workshops on CMT and participated into two other workshops.
He organized the 6th International meeting of the Charcot-Marie-Tooth and Related neuropathies consortium (CMTR) in Mestre-Venice, 8-10th Sept. 2016.
He has co-authored 228 papers on peer-reviewed Journals (Pubmed) mainly on hereditary disorders and neuromuscular diseases. H-index = 40 (Scopus)