Institute of Experimental Neurology, San Raffaele Hospital, Milan

Carla Taveggia

Biosketch

Carla Taveggia graduated in Biology at the University of Milan and obtained her Ph.D. in Molecular and Cellular Biology at the Open University London, UK. She then moved in New York, US at the NYU Medical Center, where she investigated, the role of the axonal molecules controlling myelination. Her studies demonstrated that Neuregulin1 type III is an essential instructive signal for PNS myelination as its axonal dosage regulates the amount of myelin produced.
In 2007 she was awarded a Transition Career Award from Federazione Italiana Sclerosi Multipla. She thus moved back to Italy in 2008, to establish her research group at the San Raffaele Scientific Institute in Milan, where she has been since then. Here, she is Group Leader and Head of the Axo-Glia Interaction Unit and since 2017 Deputy Director of the Division of Neuroscience.
At San Raffaele Scientific Institute she continued to study the mechanisms controlling neuronal glial communication and identified the secretase TACE as a posttranscriptional regulator of Neuregulin1 cleavage and activity. More recently, her laboratory identified in Prostaglandin D2 synthase and its signaling mechanism a novel pathway regulating PNS myelin formation and maintenance.